李建林
师资介绍
李建林,男,汉族,1980.11,教授,博士
研究方向:
天然药物化学
先后主持并结题了:
国家自然科学基金委员会,青年项目,三株海洋共附生细菌外排泵抑制剂活性成分研究
中国博士后基金项目,海洋真菌中血管内皮生长因子受体抑制剂活性成分研究
江苏省博士后基金项目,基于诱导沉默基因激活的深海真菌的抗菌活性成分研究
南通市科技局项目,基于诱导沉默基因激活及液质联用技术分析策略的两株深海真菌的新型抗生素活性成分研究
南通市科技局项目,海洋共附生细菌中的抗菌活性成分研究
科研成果:
授权专利:
1、双吲哚类衍生物及其制备方法与应用. 中国专利,专利号:ZL201510037124.1
2、异普耳文酸衍生物及其制备法与应用. 中国专利,专利号:ZL201710049877.3
代表性论文:
1)Jian Lin Li*, Lai-Lai Wei, Chen Chen, Di Liu, Yu-Qin Gu, Jia-xin Duan-Mu, Guang-tong Chen, Yan Song*, Bioactive Constituents from the Bryophyta Hypnum plumaeforme, Chemistry & Biodiversity, 2020, 17, e2000552.
2) Lai-Lai Wei, Min Yang, Lei Huang*, Jian Lin Li*, Antibacterial and antioxidantfavonoid derivatives from the fruits of Metaplexis aponica, Food Chemistry, 2019, 289, 308-312.
3) Jian LinLi, Xin Jiang, Xinpei Liu, Caiwei He, Yuxin Di, Saijian Lu, Huilian Huang, Bin Lin, Dong Wang*, Boyi Fan*, Antibacterial anthraquinone dimers from marine derived fungus Aspergillus sp, Fitoterapia, 2019, 133: 1-4.
4) Jian Lin Li, Ningjing Yang, Lei Huang, Dandan Chen, Yu Zhao, M. Matt Tang, Huizhou Fan, Xiaofeng Bao*, Pyocyanin Inhibits Chlamydia Infection by Disabling Infectivity of the Elementary Body and Disrupting Intracellular Growth, Antimicrobial Agents and Chemotherapy, 2018, 62, e02260-17.
5) Yuqin Gu, Peiyu Ding, Zhipeng Liang, Yan Song, Yonghong Liu, Guangtong Chen*, Jian Lin Li*, Activated production of silent metabolites from marine-derived fungus Penicillium citrinum. Fitoterapia, 2018, 127, 207-211.
6) Jian Lin Li, Dandan Chen, Lei Huang, Min Ni, Yu Zhao, Huizhou Fan*, Xiaofeng Bao*, Antichlamydial Dimeric Indole Derivatives from Marine Actinomycete Rubrobacter radiotolerans. 2017, 83, 805-811.