方桂花
师资介绍
方桂花,女, 1990年9生,药剂学博士,yl6809永利官网,讲师
研究方向:
口服递药,眼部新型给药系统,缓控释制剂
基金项目:
南通市自然科学基金,JC2019100,基于胆酸吸收途径的口服纳米递药系统构建及治疗肝癌的研究,2019-07 至 2021-06,3万元,已结题,主持
江苏省高校自然科学研究面上项目,18KJB350009,粘附性高载药量脂质载体应用于胰岛素口服传递研究,2018-07 至 2020-06,3万元,已结题,主持
江苏省自然科学基金(青年项目),BK20170445,靶向新型有机阳离子转运体的眼用前药递送系统的研究, 2017-07 至 2020/06,20万,已结题,参加
代表性论文:
(1) Fang Guihua and Tang Bo*, Current advances in nano-delivery of celastrol for treating inflammation associated diseases, Journal of Materials Chemistry B, 2020, 8(48), 10954-10965.
(2) Fang Guihua, Tang Bo*, Advanced delivery strategies facilitating oral absorption of heparins, Asian Journal of Pharmaceutical Sciences, 2020, 15(4), 449-460.
(3)Tang Bo, Qian Yu, Fang Guihua*. Development of Lipid-Polymer Hybrid Nanoparticles for Improving Oral Absorption of Enoxaparin. Pharmaceutics, 2020, 12(7), 607-618.
(4) Tang Bo, Qian Yu, Gou Yi, Cheng Gang, Fang Guihua*, VE-Albumin Core-Shell Nanoparticles for Paclitaxel Delivery to Treat MDR Breast Cancer. Molecules, 2018, 23, 2760.
(5) Fang Guihua, Zhou Jing, Qian Yu, Gou Jingxin, Yang Xiang, Tang Bo*, Development and evaluation of thermo-sensitive hydrogel system with nanocomplexes for prolonged subcutaneous delivery of enoxaparin, Journal of Drug Delivery Science and Technology, 2018, 48 (2018), 118-124.
(5) Fang Guihua, Tang Bo, Chao Yanhui, Xu Helin, Gou Jingxin, ZhangYu, Xu Hui, Tang Xing*,Cysteine-functionalized nanostructured lipid carriers for oral delivery of docetaxel: A permeability and pharmacokinetic study. Molecular Pharmaceutics, 2015, 12 (7), 2384-2395.
(6) Fang Guihua, Tang Bo, Chao Yanhui, Zhang Yu*, Xu Hui, Tang Xing*, Improved oral bioavailability of docetaxel by nanostructured lipid carriers: in vitro characteristics, in vivo evaluation and intestinal transport studies. RSC Advances, 2015, 5(117), 96437-96447.
(7) Fang Guihua, Tang Bo, Liu Zitong, Gou Jingxin, ZhangYu, Xu Hui, Tang Xing*. Novel hydrophobin-coated docetaxel nanoparticles for intravenous delivery: in vitro characteristics and in vivo performance. European Journal of Pharmaceutical Sciences, 2014, 60, 1-9.