药物制剂系

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王伟奇

作者:金飞     日期:2023-10-11   点击数:2442  

师资介绍

王伟奇,女,汉,1990年11生,副教授,理学博士

研究方向:

纳米药物

基金项目:

1.国家自然科学基金青年项目,基于纳米CpG-MOFs的化学动力疗法与巨噬细胞调控研究,2020.01-2022.1224.00万元,结题,主持;

2. 南通市科技计划项目,黄芪四君子汤联合辐射光动力治疗原位肝癌及其作用机制的研究,2018.07-2020.073.00万元,结题,主持;

3. 江苏省高等学校自然科学研究面上项目,阻断免疫检查点增强光动力抗肿瘤免疫逃逸的研究,2018.09-2020.083.00万元,结题,主持;

  科研成果:

  代表性论文

1.       Mengjiao Zhou, Minjian Yuan, Yilan Jin, Qianqian Zhou, Yuting Yu, Jianan Li, Xing Dai, Xiaohua Zheng, Haijun Yu*, Weiqi Wang*, Vitamin B2-based ferroptosis promoter for sono-enhanced nanocatalytic therapy of triple-negative breast cancer. Advanced Functional Materials 2023, 2303899.

2.       Weiqi Wang, Qiwen Zhu, Yilan Jin, Jing Gao, Jianan Li, Xiaohua Zheng,Weidong Gao, Madiha Saeed,*Weizhong Sheng,* and Haijun Yu* Self-immolated nanoadjuvant for in situ vaccination immunotherapy of colorectal cancer. Advanced Healthcare Materials 2023,12, 2300524.

3.       Yanting Shi, Yutao Zou, M. Shahnawaz Khan, Mengge Zhang, Jiang Yan, Xiaohua Zheng,* Weiqi Wang,* Zhigang Xie,*Metal-organic framework-derived photoelectrochemical sensors: structural design and biosensing technology.Journal of Materials Chemistry C 2023, 11, 3692

4.       Weiqi Wang, Yuting Yu, Yilan Jin, Xiao Liu, Min Shang, Xiaohua Zheng*, Tingting Liu* and Zhigang Xie*Two-dimensional metal-organic frameworks: from synthesis to bioapplications.Journal of Nanobiotechnology 2022, 20, 207.

5.       DingYi Fu, Xiao Liu, Xiaohua Zheng, Mengjiao Zhou, Weiqi Wang,* Gaoxing Su, Tianqing Liu, Lei Wang, Zhigang Xie,* Polymer-metal-organic framework hybrids for bioimaging and cancer therapy, Coordination Chemistry Reviews 2022, 456, 214393.

6.       Weiqi Wang, Yilan Jin, Xiao Liu, Fangmin Chen, Xiaohua Zheng, Tianqing Liu, Yumin Yang*, Haijun Yu,* Endogenous Stimuli-activatable nanomedicine for immune theranostic of cancer, Advanced Functional Materials 2021, 31, 2100386.

7.       Xiaohua Zheng, Yilan Jin, Xiao Liu, Tianqing Liu, Weiqi Wang,* Haijun Yu,* Photoactivatable nanogenerators of reactive species for cancer therapy, Bioactive Materials 2021, 6, 4301.

8.       Mengjiao Zhou, Xiao Liu, Fangmin Chen, Lili Yang, Minjian Yuan, Ding-Yi Fu, Weiqi Wang*, Haijun Yu*, Stimuli-activatable nanomaterials for phototherapy of cancer. Biomedical Materials 2021, 16, 042008.

9.       Jiaxin Wang, Mengxue Zhou, Fangmin Chen, Xiao Liu, Jin Gao, Weiqi Wang, Hui Wang, Haijun Yu,Stimuli-sheddable nanomedicine overcoming pathophysiological barriers for potentiating immunotherapy of cancer. Journal of Biomedical Nanotechnology, 2021, 17, 1486.

10.   Xiao Liu, Yilan Jin, Tingting Liu, Shengju Yang, Mengjiao Zhou, Weiqi Wang,* Haiju Yu,* Iron-based theranostic nanoplatform for improving chemodynamic therapy of cancer. ACS Biomaterials Science & Engineering 2020, 6, 4834.

11.   Weiqi Wang, Yilan Jin, Zhiai Xu, Xiao Liu, Sadia Z. Bajwa, Waheed S. Khan, Haijun Yu,* Stimuli-activatable nanomedicines for chemodynamic therapy of cancer. Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology 2020, e1614.

12.   Zhihao Zhao,# Weiqi Wang,# Chenxi Li, Yiqiu Zhang, Tianrong Yu, Renfei Wu, Jiayue Zhao, Zhuang Liu, Jian Liu,* Haijun Yu,* Reactive oxygen species-activatable liposomes regulating hypoxic tumor microenvironment for synergistic photo/chemodynamic therapies. Advanced Functional Materials 2019, 1905013.

13.   Weiqi Wang, Madiha Saeed, Yao Zhou, Lili Yang, Dangge Wang, Haijun Yu,* Non-viral gene delivery for cancer immunotherapy. Journal of Gene Medicine 2019, 21, e3092.

14.   Weiqi Wang, Lei Wang, Shi Liu, Zhigang Xie,* Xiabin Jing. Metal-organic frameworks@polymer composites containing cyanines for near-infrared fluorescence imaging and photothermal tumor therapy. Bioconjugated Chemistry 2017, 28, 2784.

15.   Weiqi Wang, Lei Wang, Yang Li, Shi Liu, Zhigang Xie,* Xiabin Jing, Nanoscale polymer-metal-organic frameworks hybrids for effective photothermal therapy of colon cancers, Advanced Materials 2016, 28, 9320.

16.   Weiqi Wang, Lei Wang, Zhensheng Li, Zhigang Xie*, BODIPY-containing nanoscale metal-organic framework for photodynamic therapy, Chemical Communications 2016, 52, 5402.

17.   Weiqi Wang, Lei Wang,* Yubin Huang, Zhigang Xie,* and Xiabin Jing. Nanoscale metal-organic framework-hemoglobin conjugates. Chemistry-An Asian Journal 2016, 11, 750-756.

18.   Weiqi Wang, Shi Liu, Yubin Huang, Xiabin Jing, Zhigang Xie,* Biodegradable dextran vesicles for effective haemoglobin encapsulation. Journal of Materials Chemistry B 2015, 3, 5753-5759.