药物制剂系

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易玄

作者:金飞     日期:2023-10-18   点击数:2536  

师资介绍




姓名:易玄

性别:男

民族:汉族

出生年月:198911

职称:教授

学历:博士研究生

研究方向:

1.放射性药物的制备及其在肿瘤诊疗中的运用;

2.基于生物材料的肿瘤放射-免疫治疗研究;

3.具有辐射防护性能的生物材料的构建及其药理学研究。

科研项目:

1.国家自然科学基金青年项目: 99mTc引导并增强仿生纳米颗粒对乳腺癌胸壁转移或复发的热消融及其机制研究,2020-012022-1222万元,结题,主持

2.国家自然科学基金委-中科院大科学装置联合基金培育项目:重离子放疗协助免疫调节性囊泡对脑胶质瘤的靶向递送和免疫治疗及其机制研究,2021-012023-1260万元,在研,主持

代表性论文:

(1) Rui Qian, Xuan Yi*, Teng Liu, Hua Chen, Yuhong Wang, Lin Hu, Lingchuan Guo, Kai Yang*, and Haijun Deng*, Regulation of Ion Homeostasis for Enhanced Tumor Radio-Immunotherapy, Advanced Science, 2023, 2304092.

(2) Jingyu Gu, Xinpei Liu, Zhongfang Ji, Mengling Shen, Minqian Zhu, Yuanyuan Ren, Li Guo, Kai Yang, Teng Liu,* and Xuan Yi*, Tumor Vascular Destruction and cGAS-STING Activation Induced by Single Drug-Loaded Nano-Micelles for Multiple Synergistic Therapies of Cancer, Small, 2023, 2303517.

(3) Hailin Zhou, Yanxiang Zhang, Pei Pei, Wenhao Shen, Xuan Yi*, Kai Yang*, Liposome-anchored mesenchymal stem cells for radiation pneumonia/fibrosis treatment, Biomaterials, 2023, 300, 122202.

(4) Pei Pei, Yu Zhang, Yunchun Jiang, Wenhao Shen, Hua Chen, Sai Yang, Yanxiang Zhang, Xuan Yi*, and Kai Yang*, Pleiotropic Immunomodulatory Functions of Radioactive Inactivated Bacterial Vectors for Enhanced Cancer Radio-immunotherapy, ACS Nano, 2022, , 16, 11325−11337.

(5) Xuan Yi, Hailin Zhou, Yu Chao, Saisai Xiong, Jing Zhong, Zhifang Chai, Kai Yang*, Zhuang Liu*, Bacteria-triggered tumor-specific thrombosis to enable potent photothermal immunotherapy of cancer, Science Advances, 2020; 6, eaba3546.